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Gene expression profile in the tethered Nrf1-MafG (T-N1G) heterodimer-expressing small Maf-deficient cells [RNA-seq]

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE188787
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To elucidate the function of Nrf1-small Maf heterodimer, we constructed a tethered Nrf1-MafG (T-N1G) heterodimer using a flexible linker peptide and examined its function in the small Maf-deficient mouse embryonic fibroblast (MEF). polyA RNA-seq was performed using RNA from immortalized MafF-/-::MafG-/-::MafK-/- (F0G0K0) MEFs and T-N1G-expressing F0G0K0 MEFs, treated with Vehcle, 0.3 µM or 1.0 µM Proteasome Inhibitor (MG132) for 12hr.
创建时间:
2022-02-09
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