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DMSO control and DZNep treated MOLM-14 cells. Homo sapiens

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA143569
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资源简介:
We demonstrated that 3-Deazaneplanocin A (DZNep), a histone methyltransferase inhibitor, induce robust apoptosis in AML cells through increased ROS production and ER stress. We identified a core gene signature including TXNIP, a major redox control molecule which is crucial in DZNep-induced apoptosis. Overall design: MOLM-14 cells were treated with DMSO and DZNep 2 µM for 24 hours
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2011-07-01
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