Mutations from IPEX patients elicit a range of phenotypes in mice [RNAseq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE225891
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资源简介：
RNAseq analysis of mouse Treg from Foxp3 missense mutant mice hemizygous male and heterozygous female : R51Q, C168Y, K199del, R309Q, F324L, R337Q Mouse CD4+ regulatory Tregs in 6-10 weeks old Foxp3 missense mutant mice hemizygous male and heterozygous female were isolated from spleen by flow cytometry, as DAPI–CD19-TCRβ+CD4+CD25+. 1,000 cells were double-sorted directly into lysis buffer for RNA-seq (Smart-seq2) library preparation following the standard ImmGen low-input protocol (www.immgen.org).
创建时间：
2023-10-20
