Gene Expression profiles of normal and inflamed colon tissues from Nik+/+, NikΔIE. Mus musculus

To investigate the detailed molecular mechanisms for the regulatory role of Nik in colitis, microarray gene expression analysis was performed on colon tissue RNA isolated from 3-month-old untreated control and DSS treated Nik+/+ and NikΔIE mice. Overall design: Global gene expression profiling in colon tissue RNAs isolated from 3-month-old Nik+/+, (n=4; shah026, control; shah028, DSS) and NikΔIE (n=4; shah027, Control; shah029, DSS).