Clusters derived from hierarchical clustering of 21-mer Jaccard similarity are predominantly composed of named taxons.

Clusters which have a majority of genera representatives from the same taxon are labeled with the corresponding taxon name (column 3) and taxon level (column 4). The number of genera that belong to the taxon and are in the cluster is given (column 5), as well as the total size of the cluster (column 6), the genus range (column 2; from S1 Table), and the total genera (out of 1634 representatives) that belong to the taxon. Named clusters, readily visualized in the heatmap of Fig 4, were labelled and numbered with a Heatmap/group ID (column 1). If multiple clusters from different subtrees (top of Fig 4) have the same taxon name, then a number is added to the name to disambiguate, unless these clusters are neighboring in the ordered list, as is the case for Proteobacteria-2 (Heatmap ID/group 27). (XLSX)