SNPs associated with Alzheimer’s disease risk.

Abbreviations: SNPs, single nucleotide polymorphisms; Chr, chromosome; n, number of cases; MAF, minor allele frequency; OR, odds ratio; CI, confidence interval; 0ε4, APOE ε4 allele noncarriers; 1ε4, carriers of 1 APOE ε4 allele; 2ε4, carriers of 2 APOE ε4 alleles.
Multiple comparison analysis (overall) was calculated by Pearson chi-square test. Univariate and multivariate analyses were calculated using binary logistic regression assuming a dominant model. Multivariate analyses were adjusted for age, sex and APOE-ε4 status. Analyses testing APOE adjusted for age and gender. Results for APOE are shown for comparative purposes.
aSignificant at false discovery rate adjusted P<0.05.
bNot significant after false discovery rate correction.
cMinor allele frequency not computed because APOE is tri-allelic.