Age-Dependent Transcriptional Alterations in Cardiac Endothelial Cells [scRNA-seq]
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=52c7f47d89ee89b5efc3326661a2db7e
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Purpose: The goal of this study is to determine alterations in heart endothelial cell transcripts and cell populations associated with aging.Methods: Endothelial single cell mRNA profiles of 3 month and 24 month old wild-type mice were generated by 10X GenomicsResults: Using an optimized data analysis workflow, we mapped about 50 thousand reads per cellConclusions: Our study represents the first analysis of aged cardiac endothelial cell transcriptomes using single cell RNA-seq technology, identifiying specific transcripts and cell populations affected by age.
提供机构：
OHSU
创建时间：
2022-02-20
