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A Simple, Two-Step, Site-Specific Preparation of Fluorinated Naphthalene and Phenanthrene Derivatives from Fluorobromo-Substituted Alkenes

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NIAID Data Ecosystem2026-03-06 收录
下载链接:
https://figshare.com/articles/dataset/A_Simple_Two_Step_Site_Specific_Preparation_of_Fluorinated_Naphthalene_and_Phenanthrene_Derivatives_from_Fluorobromo_Substituted_Alkenes/3056866
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A facile two-step procedure for the site-specific preparation of fluorinated naphthalene and phenanthrene derivatives is described. The Sonogashira reaction of bromofluoro-substituted alkenes with terminal alkynes, followed by base-catalyzed cyclization in refluxing N-methyl-2-pyrrolidinone (NMP), affords the corresponding fluorinated naphthalene and phenanthrene derivatives in good yields.
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2006-09-29
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