Characterization of neuroendocrine tumors in heterozygous mutant MENX rats: a novel model of invasive medullary thyroid carcinoma [adrenal]
收藏Alliance of Genome Resources2026-08-01 收录
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We here show that the reduction to a single functional p27 allele predisposes MENX heterozygous rats to the development of neuroendocrine malignancies.
本研究证实，仅保留单个功能性p27等位基因（p27 allele）可使MENX杂合子大鼠罹患神经内分泌恶性肿瘤的风险显著增加。
