Supplementary Material for: Predictors of Postoperative Non-Chylous Massive Discharge after Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma

Background: Pancreaticoduodenectomy (PD) is performed
for pancreatic ductal adenocarcinoma (PDA) located at the pancreas
head/body. Non-chylous massive discharge after PD is frequently
encountered and can cause a vicious cycle of complications associated
with severe dehydration and protein loss. Methods: From
August 2008 to June 2015, 102 patients who underwent PD for PDA were
retrospectively reviewed. High non-chylous discharge was defined as
postoperative daily serous discharge exceeding 10 mL/kg. Predictive
factors for high non-chylous discharge were assessed using multivariable
analysis. Results: Fifty-one patients (50%) developed
high non-chylous discharge. Body mass index (BMI) and hemoglobin, total
protein, and cholinesterase levels were significantly lower in the
high-discharge group compared to the corresponding levels in the
low-discharge group. The incidence of postoperative pancreatic fistula
and delayed gastric emptying was significantly lower and higher in the
high-discharge group than in the low-discharge group, respectively.
Multivariable analysis revealed that BMI

背景：胰腺十二指肠切除术（PD）用于治疗位于胰腺头部/体部的胰腺导管腺癌（PDA）。胰腺十二指肠切除术后的非胆汁性大量排出物在临床实践中较为常见，且可能导致与严重脱水和蛋白质流失相关的并发症恶性循环。方法：自2008年8月至2015年6月，对102例接受PD治疗的PDA患者进行了回顾性分析。高非胆汁性排出物被定义为术后每日血清排出量超过10 mL/kg。采用多变量分析评估高非胆汁性排出物的预测因素。结果：51例患者（50%）发生了高非胆汁性排出物。与低排出组相比，高排出组的体重指数（BMI）、血红蛋白、总蛋白和胆碱酯酶水平显著降低。术后胰腺瘘和胃排空延迟的发生率在高排出组分别显著低于和高于低排出组。多变量分析显示，BMI