BACE crystal structure with hydroxy pyrrolidine inhibitor
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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BACE crystal structure with hydroxy pyrrolidine inhibitor Descriptor: 2-{[(2S)-butan-2-yl]amino}-N-{(1R,2S)-1-hydroxy-3-phenyl-1-[(2R)-pyrrolidin-2-yl]propan-2-yl}-6-(methylsulfonyl)pyridine-4-carboxamide, Beta-secretase 1, GLYCEROL Authors: Timm, D.E. Deposit date: 2017-10-26 Release date: 2017-11-15 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences. J. Med. Chem., 60, 2017
创建时间：
2017-10-26
