Ability of membTF mutants to support activation of FX and FIX, and clotting of plasma.

aData are mean ± standard deviation of normalized rates of FX and FIX activation, and clotting activities, using membTF mutants in 5% PS/95% PC vesicles. Eight mutants selected for study are boldfaced.bNot determined.cKirchhofer et al. [3], using sTF with either SW-13 cell membranes or 500 µM 70% PS/30% PC liposomes.dRuf et al. [24], using detergent lysates of cells transfected to express membrane-anchored TF.eRehemtulla et al. [32], using detergent lysates of cells transfected to express membrane-anchored TF.fRoy et al. [30], using detergent lysates of cells transfected to express membrane-anchored TF, diluted in a buffer with 100% PC vesicles.gRuf et al. [31], using detergent lysates of cells transfected to express membrane-anchored TF.