Quantitative Proteomic Verification of Membrane Proteins as Potential Therapeutic Targets Located in the 11q13 Amplicon in Cancers.

Data from ProteomeXchange, PXD ID: PXD002486. Experiment: 11q13_group3_HHn1, file: folder summary. Published as part of J Proteome Res. 2015 Jul 29 . From the Abstract: {{i}} ... We employed a tandem mass spectrometry proteomics approach using tumor cell lines to identify the cell surface proteins whose expression correlates with the 11q13 amplicon. The 11q13 amplicon is one of the most frequently amplified chromosomal regions in human cancer, being present in 45% of head and neck and oral squamous cell carcinoma (OSCC) and 13-21% of breast and liver carcinomas ... {{/i}}