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Domino Formation of Enamines - Intramolecular Cyclizations to 1‑Aminotetralins from γ‑Arylallene Aldehydes and Amines

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https://figshare.com/articles/dataset/Domino_Formation_of_Enamines_Intramolecular_Cyclizations_to_1_Aminotetralins_from_Arylallene_Aldehydes_and_Amines/2244355
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资源简介:
1,5-/1,6-Allenals conjugated to an aromatic ring undergo a cyclization, in the presence of an amine, that leads to tricyclic compounds including the 1-aminotetralin scaffold. This domino process combines the in situ formation of the enamine and the cyclization affording the tricyclic 1-aminotetralins in very high diastereoselectivities.
创建时间:
2016-02-16
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