Cryo-EM structure of the human TREX-2.1 complex (LENG8/PCID2/DSS1) bound to the N-terminal motif of DDX39B(UAP56)

Cryo-EM structure of the human TREX-2.1 complex (LENG8/PCID2/DSS1) bound to the N-terminal motif of DDX39B(UAP56) Descriptor: 26S proteasome complex subunit SEM1, Leukocyte receptor cluster member 8, PCI domain-containing protein 2, ... Authors: Clarke, B.P, Xie, Y, Ren, Y. Deposit date: 2024-09-11 Release date: 2025-09-17 Last modified: 2025-11-12 Method: ELECTRON MICROSCOPY (3.08 Å) Cite: Structural mechanism of DDX39B regulation by human TREX-2 and a related complex in mRNP remodeling. Nat Commun, 16, 2025