ToxicoDB: an integrated database to mine and visualize large-scale toxicogenomic datasets (TGGATEs human dataset)

This data was generated by Igarashi Y, Nakatsu N, Yamashita T, Ono A, Ohno Y, Urushidani T, Yamada H. Open TG-GATEs: a large-scale toxicogenomics database. Nucleic Acids Res [Internet]. 2015 Jan;43(Database issue):D921–7. Available from: http://dx.doi.org/10.1093/nar/gku955 PMCID: PMC4384023. The data have been curated and analyzed using our open-source R package, ToxicoGx (https://bioconductor.org/packages/devel/bioc/html/ToxicoGx.html), and are available publicly in the ToxicoDB web application (www.toxicodb.ca).

搜集汇总

背景与挑战

背景概述

该数据集是基于Open TG-GATEs大规模毒理基因组学数据库的人类数据集，通过ToxicoGx R包进行整理和分析，并集成到ToxicoDB网络应用中，用于挖掘和可视化毒理基因组数据。数据集包含人类DNA对应活力测量，专注于毒理基因组学领域，旨在支持药物毒性研究。