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Human p38 MAP Kinase in Complex with Scios-469

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Human p38 MAP Kinase in Complex with Scios-469 Descriptor: 2-(6-chloro-5-{[(2R,5S)-4-(4-fluorobenzyl)-2,5-dimethylpiperazin-1-yl]carbonyl}-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside Authors: Gruetter, C, Simard, J.R, Rauh, D. Deposit date: 2009-06-13 Release date: 2010-03-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Fluorophore labeling of the glycine-rich loop as a method of identifying inhibitors that bind to active and inactive kinase conformations. J.Am.Chem.Soc., 132, 2010
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2009-06-13
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