File S1 - Chemically Defined Diet Alters the Protective Properties of Fructo-Oligosaccharides and Isomalto-Oligosaccharides in HLA-B27 Transgenic Rats

Figure S1. Linear discriminant analysis for cecal (Panel A) and fecal (Panel B) samples. Analysis was performed based on gene copy numbers of bacterial groups. HLA-B27 transgenic rats were fed a AIN-76A diet (indicated with A) or a rat chow diet (indicated with R). Diets were supplemented with fructo-oligosaccharides (FOS; □, ▪) or with isomalto-oligosaccharides (IMO; Δ, ▴), or not supplemented with oligosaccharides (control; ○, •) for a period of 12 weeks. Each symbol represents an individual animal. Numbers represent variables discriminating between the groups as follows: 1, Bacteroides group; 2, Lactobacillus group; 3, Bifidobacterium spp.; 4, Enterobacteriaceae family; 5, Clostridium cluster I; 6, Clostridium cluster IV; 7, Clostridium cluster XIVa; 8, Butyryl-CoA transferase gene; 9, Butyrate-kinase gene; 10, Clostridium cluster XI; 11, Clostridium difficile toxin B. Table S1. Basic composition of chemically defined diet (AIN-76A). Table S2. Chemical composition of rat chow diet (5053 PicoLab Rodent Diet 20). (PDF)