Discovery of ASTX029, a clinical candidate which modulates the phosphorylation and catalytic activity of ERK1/2
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Discovery of ASTX029, a clinical candidate which modulates the phosphorylation and catalytic activity of ERK1/2 Descriptor: (2~{R})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-2-oxidanyl-ethyl]propanamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... Authors: O'Reilly, M, Cleasby, A. Deposit date: 2021-03-03 Release date: 2021-10-06 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.627 Å) Cite: Discovery of ASTX029, A Clinical Candidate Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2. J.Med.Chem., 64, 2021
创建时间：
2021-03-03
