Chirality and Fragrance Chemistry: Stereoisomers of the Commercial Chiral Odorants Muguesia and Pamplefleur

The work describes the enzyme-mediated preparation and the odor evaluation of the single
stereoisomers of the commercial odorants Muguesia and Pamplefleur. The synthetic approach to
Muguesia stereoisomers helped to clear the assignment of the relative configuration of intermediate
diols 5. The odor response of Pamplefleur isomers was found to be rather unusual. No stereoisomer
prevailed, but each one played a definite role in establishing the odor sensation of the final blend.