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Crystal structure of dipeptidyl peptidase IV in complex with a pyrimidinedione inhibitor 2

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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Crystal structure of dipeptidyl peptidase IV in complex with a pyrimidinedione inhibitor 2 Descriptor: 2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Zhang, Z, Wallace, M.B, Feng, J, Stafford, J.A, Kaldor, S.W, Shi, L, Skene, R.J, Aertgeerts, K, Lee, B, Jennings, A, Xu, R, Kassel, D, Webb, D.R, Gwaltney, S.L. Deposit date: 2009-01-27 Release date: 2010-02-16 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV. J.Med.Chem., 54, 2011
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2009-01-27
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