Proportion of associations reported as significant () using different methods of stratification correction for simulated data.
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https://figshare.com/articles/dataset/_Proportion_of_associations_reported_as_significant_using_different_methods_of_stratification_correction_for_simulated_data_/500598
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aStruInfo SNPs: Allele frequencies were simulated based on the Balding-Nichols model and the SNPs were population structure informative.
bSpecific SNPs: Allele frequencies of the populations were fixed to the specified values: (proportional to the ratio of the sample sizes) or (inversely proportional to the ratio of the sample sizes).
cCausal: Genotypes were generated according to the proportion: where is the causal allele frequency and is the relative risk.
dNull: Genotypes were generated according to the Hardy-Weinberg proportion: . SNPs were simulated for each of the categories.
创建时间:
2010-09-17



