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Immune biological differences between Triple Negative Breast Cancer in African

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NIAID Data Ecosystem2026-03-12 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA704957
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资源简介:
This study aims to compare the immune microenvironment of newly diagnosed, stage I-III, triple negative breast cancer (TNBC) in African American (AA) and non-AA women, correlate differences, if any, with the somatic genomic landscape of the cancer, and test if addition of an anti-PDL1 antibody (MEDI4736) to weekly nab-paclitaxel followed by dose dense doxorubicin/cyclophosphamide chemotherapy could increase Pathologic Complete Response (pCR) rates in a prospective clinical trial and assess if this benefit differs by race.
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2021-02-25
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