Nicotabin A, a Sesquiterpenoid Derivative from Nicotiana tabacum
收藏Figshare2017-09-19 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Nicotabin_A_a_Sesquiterpenoid_Derivative_from_i_Nicotiana_tabacum_i_/5384350
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资源简介:
Nicotabin A (1), a sesquiterpenoid derivative possessing a fused 5/6/5/5/5 ring system, was isolated from leaves of Nicotiana tabacum. The structure was elucidated by extensive spectroscopic methods and confirmed by single crystal X-ray diffraction. The plausible biosynthetic pathway for 1 was proposed. Compound 1 inhibited nitric oxide production in LPS-activated RAW264.7 macrophages with an IC50 of 22.1 μM.
创建时间:
2017-09-19



