Minor allele frequency of HBB and IRF1 Single Nucleotide Polymorphisms (SNPs) in trio parents from The Gambia, Kenya and Malawi.

The table shows the SNPs that have been genotyped in the affected child parental trio studies and their frequency in trio parents from The Gambia, Kenya and Malawi. These are not unbiased estimates of the population frequencies. Chr coord is the SNP chromosome coordinate (chromosome: base pair) based on Ensemble release 40. Location: location of the SNP with respect to the HBB or IRF1 locus. Alleles: minor and major alleles (major allele is shown in brackets). MAF: Minor Allele Frequency in pedigree parents (The Gambia, N = 1100; Kenya, N = 408; Malawi, N = 404). StE: Standard Error of the MAF. MAF comparison: P-values of Yates corrected χ2 Test for comparison of MAF between populations; a P-value