The Data Analysis item Screening of patient report outcome measurement scale in idiopathic pulmonary fibrosis

In order to develop the PRO scale for IPF patients with Chinese characteristics, Delphi expert consultation method and IPF patients clinical questionnaire survey method will be used to screen the items of the scale. This data is the relevant data obtained from the expert importance scoring and effective clinical questionnaire. The items collected in the early stage are made into an expert consultation questionnaire, and each expert independently scores the importance of the items in the questionnaire. The critical value is determined by the average value and standard deviation of the three indexes: The average value, Coefficient of variation and unimportant percentage of each item. Deletion criteria include items with average value less than critical value, items with coefficient of variation greater than critical value, and items with unimportant percentage greater than critical value. Items meeting the above two or more deletion criteria will be deleted. The primary scale formed after expert consultation and statistics will be made into a clinical questionnaire and distributed to IPF patients. The questions of each item are mostly expressed in frequency or degree. Using Likert 5-grade scoring method, the choice grade is from light to heavy, and 1-5 points are calculated in turn. The recovered effective questionnaires will be analyzed by six statistical methods: item distribution survey method, discrete trend method, Cronbach coefficient method, correlation coefficient method, factor analysis method and multivariate linear regression analysis method, and items that met three or more deletion criteria in the six screening methods will be intended to be deleted.

为构建具有中国特色的IPF（特发性肺纤维化）患者PRO量表，将采用德尔菲专家咨询法和IPF患者临床问卷调查法筛选量表条目。本数据集包含了从专家重要性评分和有效临床问卷调查中获取的相关数据。早期收集的条目被编制成专家咨询问卷，每位专家独立对问卷中条目的重要性进行评分。临界值由三个指标的平均值和标准差确定：平均值、变异系数和各条目的不重要百分比。删除标准包括平均值低于临界值的条目、变异系数高于临界值的条目以及不重要百分比高于临界值的条目。符合上述两个或两个以上删除标准的条目将被删除。经过专家咨询和统计分析后形成的初步量表将被编制成临床问卷，并分发给IPF患者。各条目的问题多以频率或程度表达。采用Likert五级评分法，选项等级从轻微至严重，依次计算1至5分。有效的回收问卷将通过六种统计方法进行分析：条目分布调查法、离散趋势法、Cronbach系数法、相关系数法、因子分析法以及多元线性回归分析法，凡在六种筛选方法中符合三个或三个以上删除标准的条目，均拟予以删除。