X-ray Structure of PHA-00665752 bound to the kinase domain of c-Met
收藏Protein Data Bank Japan2023-12-13 更新2026-03-21 收录
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X-ray Structure of PHA-00665752 bound to the kinase domain of c-Met Descriptor: (3Z)-5-[(2,6-DICHLOROBENZYL)SULFONYL]-3-[(3,5-DIMETHYL-4-{[(2S)-2-(PYRROLIDIN-1-YLMETHYL)PYRROLIDIN-1-YL]CARBONYL}-1H-PYRROL-2-YL)METHYLIDENE]-1,3-DIHYDRO-2H-INDOL-2-ONE, HEPATOCYTE GROWTH FACTOR RECEPTOR Authors: McTigue, M, Grodsky, N, Ryan, K, Cui, J.J. Deposit date: 2009-06-15 Release date: 2010-08-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure Based Drug Design of Crizotinib (Pf-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal-Epithelial Transition Factor (C-met) Kinase and Anaplastic Lymphoma Kinase (Alk). J.Med.Chem, 54, 2011
创建时间：
2009-06-15
