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Diastereo- and Enantioselective Synthesis of 2,2-Disubstituted Benzofuran-3-one Bearing Adjacent Quaternary and Tertiary Stereocenters

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NIAID Data Ecosystem2026-03-10 收录
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https://figshare.com/articles/dataset/Diastereo-_and_Enantioselective_Synthesis_of_2_2-Disubstituted_Benzofuran-3-one_Bearing_Adjacent_Quaternary_and_Tertiary_Stereocenters/5253001
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The first highly diastereo- and enantioselective synthesis of armeniaspirol analogues was achieved using L-proline derived bifunctional squaramide which outperformed commonly used organocatalysts. Excellent yield (up to 99%) with diastereoselectivity (up to 99:1) and enantioselectivity (up to 99%) were obtained for a wide range of substrates.
创建时间:
2017-07-27
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