Transcriptomics enrichment analyses for Per1,2−/− mouse livers.

The file contains 4 tabs (A–D). Enrichment tests presented are the supporting tables for Fig 3G and 3I: Mouse ChEA dataset (A), MSigDB C3:TFT collection (B), and GO cellular component (C). The rows in tab C correspond to datasets, transcription factors, or terms significantly enriched in the Per1,2−/− liver transcriptomics. “GeneRatio”—the pathway members out of the experimental group; “BgRatio”—the total pathway size out of the reference genome size; “pvalue”—the overrepresentation test p-value; “qvalue”—the FDR of the p-value; “geneID”—the pathway members present in the experimental group; “Count”—the number of pathway members present in the experimental group. In addition, we included ingenuity upstream regulators analysis (D). Rows correspond to predicted upstream regulators in each category. “p-value of overlap”—the overrepresentation test p-value; “Molecule Type”—the type of upstream molecule (e.g., transcriptional regulator, receptor, etc.); “Target molecules in dataset”—the least of targets included in the gene category. (XLSX)