Crystal Structure of Human Mitochondrial Isocitrate Dehydrogenase R140Q Mutant Homodimer bound to NADPH and alpha-Ketoglutaric acid
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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Crystal Structure of Human Mitochondrial Isocitrate Dehydrogenase R140Q Mutant Homodimer bound to NADPH and alpha-Ketoglutaric acid Descriptor: 2-OXOGLUTARIC ACID, ACETATE ION, CALCIUM ION, ... Authors: Zhang, B, Jin, L, Wu, W, Jiang, F, DeLaBarre, B, Travins, J.A, Padyana, A.K. Deposit date: 2016-02-19 Release date: 2017-03-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.54 Å) Cite: AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations. Cancer Discov, 7, 2017
创建时间:
2016-02-19



