Genome wide mapping of histone 3 lysine 79 dimethylation in MLL-AF6 murine leukemias. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA184352
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资源简介：
We report the genome wide distribution of H3K79 dimethylation in mouse MLL-AF6 positive leukemias to assess whether this epigenetic mark drives MLL-target gene expression. Overall design: Examination of H3K79 dimethylation in bone marrow cells from sacrificed terminally ill MLL-AF6 positive leukemic mice. The retroviral MSCV-IRES-neo-MLL-AF6 construct was transduced into mouse bone marrow lineage negative Kit +, Sca + (LSK) cells and these cells were injected after G418 selection into irradiated syngenic mice to establish MLL-AF6 positive leukemias.
创建时间：
2012-12-20
