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Crystal structure of Trypanosoma cruzi farnesyl diphosphate synthase in complex with [2-(n-pentylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal structure of Trypanosoma cruzi farnesyl diphosphate synthase in complex with [2-(n-pentylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETATE ION, Farnesyl pyrophosphate synthase, ... Authors: Aripirala, S, Amzel, L.M, Gabelli, S.B. Deposit date: 2012-02-24 Release date: 2013-01-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J.Med.Chem., 55, 2012
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2012-02-24
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