Crystal Structure of small molecule disulfide 4 covalently bound to K-Ras G12C
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Crystal Structure of small molecule disulfide 4 covalently bound to K-Ras G12C Descriptor: 1-[(2,4-dichlorophenoxy)acetyl]-N-(2-sulfanylethyl)piperidine-4-carboxamide, CALCIUM ION, GTPase KRas, ... Authors: Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. Deposit date: 2013-07-26 Release date: 2013-11-27 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.5 Å) Cite: K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
创建时间：
2013-07-26
