crystal structure of BCL-2 F104L mutation with venetoclax
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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crystal structure of BCL-2 F104L mutation with venetoclax Descriptor: 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-[(3-nitro-4-{[(oxan-4-yl )methyl]amino}phenyl)sulfonyl]-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide, Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2, DI(HYDROXYETHYL)ETHER Authors: Birkinshaw, R.W, Luo, C.S, Colman, P.M, Czabotar, P.E. Deposit date: 2019-02-16 Release date: 2019-05-22 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations. Nat Commun, 10, 2019
创建时间：
2019-02-16
