Crystal structure of PqsR (MvfR) ligand-binding domain in complex with a pyridin agonist
收藏Protein Data Bank Japan2024-01-31 更新2026-03-21 收录
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Crystal structure of PqsR (MvfR) ligand-binding domain in complex with a pyridin agonist Descriptor: Transcriptional regulator MvfR, ~{N}-[3-(4-fluorophenyl)prop-2-ynyl]-2-(trifluoromethyl)pyridin-4-amine Authors: Schmelz, S, Blankenfeldt, W. Deposit date: 2021-01-28 Release date: 2021-10-06 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Divergent synthesis and biological evaluation of 2-(trifluoromethyl)pyridines as virulence-attenuating inverse agonists targeting PqsR. Eur.J.Med.Chem., 226, 2021
创建时间：
2021-01-28
