Randomised Phase II trial of de Gramont schedule 5-fluorouracil and leucovorin plus irinotecan versus single agent irinotecan in patients with previously treated metastatic colorectal cancer (DaVINCI)

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https://www.omicsdi.org/dataset/ecrin-mdr-crc/2452180

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Interventions: Irinotecan versus irinotecan + 5-FU/leucovorin. Duration: Until patients progress Primary outcome(s): Rates of Grade 3/4 diarrhoea[Every 2 weeks (combination arm) and Every 3 weeks (single agent arm) using the CTC AE Version 3.0 scale.] Study Design: Purpose: Treatment; Allocation: Randomised controlled trial; Masking: Open (masking not used);Assignment: Parallel;Type of endpoint: Safety/efficacy

创建时间：

2005-06-15