Nonmotor symptoms in patients with LRRK2 G2019S associated Parkinson’s disease, idiopathic Parkinson’s disease and healthy subjects.

LRRK2 G2019S PD: LRRK2 G2019S-related Parkinson’s disease; IPD: Idiopathic Parkinson’s disease; HS: healthy subjects. G-I: Gastro-intestinal; RBD: REM behavior disorder; EDS: excessive daytime sleepiness.#Chi-square test;±Fisher’s exact test;¶Kruskal-Wallis analysis;§Mann-Whitney U test;*Statistically significant: P0.05;1Mean ± Standard deviation (Range);2Hyposmia was arbitrarily defined as an UPSIT score lower than the mean–2 SD UPSIT score obtained in a subset of healthy subjects of the same gender and similar age.Nonmotor symptoms in patients with LRRK2 G2019S associated Parkinson’s disease, idiopathic Parkinson’s disease and healthy subjects.