The retinoic acid (RA) signaling pathway is essential for cardiac development; however, cardiomyocytes, the main cell type of the heart, are considered to be unresposive to RA signaling. The goal of t

干细胞与再生医学数据中心2022-02-20 更新50

Transcriptomic profiling of wild-type C2C12 cells and C2C12 cells with Myod1 gene knockout by RNA-sequencing. Transcriptomic profiling of wild-type C2C12 cells and C2C12 cells with Myod1 gene knockout by RNA-sequencing

肌肉分化转录组学

基因功能缺失分析

C2C12 is a myoblast cell line usually used for study of muscle differentiation. Myod1 is a pro-differentiation factor for myogenesis. We found that CRISPR/Cas9-mediated Myod1 gene knockout in C2C12 ce

NIAID Data Ecosystem30

Supplemental video

果蝇生理学

心脏发育

This is the supplemental video showing contraction of cardiac tube in Drosophila.

DataCite Commons2025-06-01 更新90

Transcriptome profiling of NGLY1 deficient K562 cells. Transcriptome profiling of NGLY1 deficient K562 cells

基因功能缺失分析

疾病转录组学

The data includes a transcriptome analysis of K562 cell lines in which the gene N-glycanase 1 (NGLY1) was mutated in exon 1 and/or exon 3 to include loss of function mutations as described in Mueller

NIAID Data Ecosystem50

HOP homeobox (Hopx) and Histone deacetylase-2 (Hdac2) deficiency effect on the embryonic heart

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