Genome Wide Characterization of Genome Organization in Mouse ES cells
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https://www.ncbi.nlm.nih.gov/sra/SRP052060
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资源简介:
The three-dimensional folding of genomes in the eukaryotic nucleus can influence the expression of genes. We used a new method to determine interactions between different chromatin regions genome-wide. Using a simple statistical model, we determine the subset of those interactions which represent stable contacts. We find an enrichment in contacts between active genes, between Polycomb-repressed genes, between enhancer elements and between enhancers and active genes. Overall design: We used a new method to detect interactions from 490 46C Mouse ES cell derived samples
创建时间:
2017-04-28



