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ROR1 sustains multivesicular endosomes by interacting with HRS and STAM1

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NIAID Data Ecosystem2026-03-12 收录
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https://www.omicsdi.org/dataset/jpost/PXD020931
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The receptor tyrosine kinase-like orphan receptor 1 (ROR1) regulates caveolae formation and caveolae-dependent endocytosis by interacting with caveolae components, which in turn sustains pro-survival signaling toward AKT from multiple RTKs, including EGFR, and MET. We report here a novel function of ROR1 as a scaffold for HRS and STAM1, two essential components of ESCRT-0.
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2021-05-27
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