官方服务：
资源简介：
Rap1a GTPase mVSM Knockout vs. Rescue Expression
应用场景：
创建时间：
2011-04-13
相关数据集
Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure
Atrial natriuretic peptide (ANP) is an important regulator of arterial blood pressure. The mechanisms mediating its hypotensive effects are complex and involve the inhibition of the sympathetic and re
PubMed Central2002-05-07 更新40
Loss of SPRR3 in ApoE -/- mice leads to atheroma vulnerability through Akt dependent and independent effects in VSMCs
Vascular smooth muscle cells (VSMCs) represent important modulators of plaque stability in advanced lesions. We previously reported that loss of small proline-rich repeat protein 3 (Sprr3), leads to V
NIAID Data Ecosystem30
Whole transcriptome analysis of mouse aortas and kidneys with or without deletion of the EGFR in vascular smooth muscle cells after 18 weeks of high fat diet
Obesity causes diabetes type 2 (DMT2) leading to vascular dysfunction and finally renal end-organ damage. Vascular smooth muscle (VSM) EGF receptor (EGFR) modulates vascular wall homeostasis in part v
NIAID Data Ecosystem20
Inducible smooth muscle specific deletion of Yap1/Wwtr1 in mouse [Thoracic aorta RNA-seq]. Inducible smooth muscle specific deletion of Yap1/Wwtr1 in mouse [Thoracic aorta RNA-seq]
YAP and TAZ are transcriptional co-activators and downstream effectors of the Hippo pathway, which play crucial roles in organ size control and cancer pathogenesis. Genetic deletion of YAP/TAZ has rev
NIAID Data Ecosystem40
YY1 regulates vascular resistance and blood pressure dynamics through epigenetic control of m6A RNA modifications in VSMCs [m6A-seq]
Background: Recent GWAS analysis has identified YY1 as a novel locus associated with blood pressure traits; however, whether YY1 directly controls vasoreactivity remains unknown. The principal functio
NIAID Data Ecosystem20
