Crystal Structure of Hck in complex with the Src-family kinase inhibitor A-419259
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Crystal Structure of Hck in complex with the Src-family kinase inhibitor A-419259 Descriptor: 1,2-ETHANEDIOL, 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, DIMETHYL SULFOXIDE, ... Authors: Selzer, A.M, Alvarado, J.J, Smithgall, T.E. Deposit date: 2024-05-23 Release date: 2024-10-09 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Cocrystallization of the Src-Family Kinase Hck with the ATP-Site Inhibitor A-419259 Stabilizes an Extended Activation Loop Conformation. Biochemistry, 63, 2024
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2024-05-23
