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Phosphatidylinositol 3-kinase modulation of trophoblast cell differentiation

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE21938
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资源简介:
Rcho-1 trophoblast stem cells can be maintained in a trophoblast stem cell state or induced to differentiate into trophoblast giant cells. During the differentiation process the PI3K pathway is constitutively activated. Microarray analysis of stem, differentiated and differentiated Rcho-1 trophoblast stem cells treated with the PI3K inhibitor LY294002. We used gene profiling to determine changes in gene expression between stem and differentiated Rcho-1 trophoblast stem cells. We also identified genes regulated by PI3K in Rcho-1 trophoblast stem cells.
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2017-07-31
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