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Rat protein geranylgeranyltransferase type-I complexed with L-778,123 and a sulfate anion

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Protein Data Bank Japan2023-08-23 更新2026-03-21 收录
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https://pdbj.org/mine/summary/1s64
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Rat protein geranylgeranyltransferase type-I complexed with L-778,123 and a sulfate anion Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE, CHLORIDE ION, ... Authors: Reid, T.S, Long, S.B, Beese, L.S. Deposit date: 2004-01-22 Release date: 2004-07-27 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Crystallographic Analysis Reveals that Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I by Different Binding Modes. Biochemistry, 43, 2004
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2004-01-22
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