Actr3

ENCODES a protein that exhibits actin binding; ATPase binding; actin filament binding (ortholog); INVOLVED IN astrocyte differentiation; cellular response to epidermal growth factor stimulus; cellular response to interleukin-1; PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH increased urine protein level; ASSOCIATED WITH Cognitive Dysfunction; focal segmental glomerulosclerosis; schizophrenia; FOUND IN actin filament; apical ectoplasmic specialization; apical tubulobulbar complex; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,4-dinitrotoluene

编码一种展现肌动蛋白结合、ATP酶结合、肌动蛋白丝结合（同源）特性的蛋白质；参与星形胶质细胞分化、细胞对表皮生长因子刺激的响应、细胞对白细胞介素-1的响应；参与胰岛素反应性促进作用糖转运蛋白介导的葡萄糖转运途径、Rab家族介导的信号通路、血小板衍生生长因子信号通路；与尿蛋白水平升高相关；与认知功能障碍、局灶节段性肾小球硬化症、精神分裂症相关；存在于肌动蛋白丝、顶端外质区、顶端管泡复合体中；与2,3,7,8-四氯二苯并-对-二氧杂蒽、2,4-二溴苯基2,4,5-三溴苯基醚、2,4-二硝基甲苯相互作用。