Interaction of Va and Vc in somatic cell reprogramming
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE142121
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资源简介：
Since VitaminA and VitaminC are pleiotropic vitamins, and both can promote reprogramming, we want to know the relationship between them. We use serum-free N2B27(B27 minus Va) medium to generate iPS with OKSM virus infecting OG2 MEF, and collect mRNA at day7 under 10nM and 1uM Va with or without Vc. We found tha both Va and Vc promote reprogramming, and the genes upregulated by Va and Va had overlpped more than 80%. To detecn the interaction of Va and Vc in MEFs during reprogramming, we collect iPS samples at day7 with Va or Vc in the medium and process with RNA-seq.
创建时间：
2020-10-27
