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Transcriptome profile of tra1 mutant in S. cerevisiae

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https://www.ncbi.nlm.nih.gov/sra/SRP310730
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Tra1 is an essential component of the SAGA and NuA4 transcriptional co-activator complexes and is linked to multiple cellular processes associated with the yeast response to antifungal drugs. This submission contains RNA sequencing data from Saccharomyces cerevisiae strains expressing a Tra1 mutant with three arginine to glutamine mutations in the PI3K domain (tra1Q3; Berg et al., 2018). Our goal was to identify how gene expression changes due to mutation to the PI3K domain of Tra1. Overall design: mRNA of strains expressing tra1Q3 compared to strains expressing wild type TRA1
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2022-05-02
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