Crystal structure of WT HIV-1 protease (NL4-3) with inhibitor J02-30
收藏Protein Data Bank Japan2026-01-07 更新2026-04-19 收录
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Crystal structure of WT HIV-1 protease (NL4-3) with inhibitor J02-30 Descriptor: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-1-(3,5-difluorophenyl)-4-[(2-ethylbutyl){4-[(1R)-1-hydroxyethyl]benzene-1-sulfonyl}amino]-3-hydroxybutan-2-yl}carbamate, Protease, SULFATE ION Authors: Kaur, J, Shaqra, A.M, Schiffer, C.A. Deposit date: 2025-08-08 Release date: 2025-12-24 Last modified: 2026-01-07 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Fluorinated HIV-1 protease inhibitors containing chiral hydroxyethylbenzene and indanol as P2' ligands with potent activity against drug-resistant variants. Eur.J.Med.Chem., 304, 2025
创建时间：
2025-08-08
