Crystal structure of HCV NS3/4A D168A protease in complex with P4-5 (NR01-97)
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Crystal structure of HCV NS3/4A D168A protease in complex with P4-5 (NR01-97) Descriptor: 1,2-ETHANEDIOL, 1-ethylcyclopentyl [(2R,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl]carbamate, NS3/4 Aprotease, ... Authors: Zephyr, J, Schiffer, C.A. Deposit date: 2019-06-27 Release date: 2020-03-04 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors. Mbio, 11, 2020
创建时间：
2019-06-27
