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Hyper-excitability of Neurons generated from Patients with Bipolar Disorder

ChEBI2015-10-30 更新2026-07-12 收录

精神疾病生物机制

神经元电生理模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-58933 数据链接链接失效反馈

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资源简介：

Hyper-excitability of Neurons generated from Patients with Bipolar Disorder

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创建时间：

2015-10-30

神经元电生理模型

神经形态计算

It is often assumed that highly-branched neuronal structures perform compartmentalized computations. However, previously we showed that the Gastric Mill (GM) neuron in the crustacean stomatogastric ga

NIAID Data Ecosystem40

tuftIB cell , dendritic input - Fortran version

计算神经科学

神经元电生理模型

Trying to reproduce A4C from Traub et al 2005 no aditional current to soma current to apical dendrite: I =3* (1-exp((t0 - t)/10)) * (exp((t0-t)/20)) we didn't get the somatic spike like in article

Figshare2016-01-18 更新40

Parameters for the sodium and potassium channels.

神经元电生理模型

离子通道参数优化

The conductance of K was changed from to to match the membrane voltage when all the spines were instantiated.

Figshare2015-12-02 更新30

Hodgkin-Huxley parameters.

神经元电生理模型

动作电位模拟

Nav and Kv parameters. Potential and time units are, respectively, mV and ms in this table. Note that G¯Na and G¯K are the maximal Nav and Kv conductances, respectively, and are taken from the origina

Figshare2015-12-03 更新40

Comparison of model properties to in vitro data.

神经元电生理模型

离子通道动力学验证

aIntrinsic STO amplitude based on variable T-type calcium conductance value ranging from 0.55 mS/cm2 to 0.9 mS/cm2. Default conductance value was 0.7 mS/cm2.bTotal calcium depolarization, including ti

Figshare2015-12-02 更新40

Hyper-excitability of Neurons generated from Patients with Bipolar Disorder

资源简介：

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